Find powerpoint presentations and slides using the power of, find free presentations research about pleomorphic adenoma ppt. Pleomorphic adenoma an overview sciencedirect topics. Adenoma is a non cancerous tumor that begins in the epithelium of mucosa or in the glands and ducts of the endocrine hormone producing glands or exocrine glands like sweat glands and glands in. Fast neutron therapy has been used successfully to treat salivary gland tumors, 10 and has shown to be significantly more effective than photons in studies treating unresectable salivary gland tumors. Carcinoma ex adenoma pleomorfico linkedin slideshare. All structured data from the file and property namespaces is available under the creative commons cc0 license. A 21yearold female referred to our clinic due to painless mass of right upper region of neck. Objectives to present the clinical presentation, workup, surgical approach, and pathological findings of the first case report of a patient with adenocarcinoma ex. In addition to carcinoma expleomorphic adenoma, true malignant mixed tumors of the salivary glands usually arise from preexisting pleomorphic adenomas 1,3. Although pleomorphic adenoma is the most common neoplasm of the salivary glands, this tumor most commonly involves the minor salivary glands of palatal and rarely occurs in cervical region. Concomitant pleomorphic adenoma of the major salivary glands is a rare but well documented occurrence. Pdf adenoma pleomorfo e carcinoma exadenoma pleomorfo.
Mri with contrast agent is the diagnostic modality of choice for the imaging of palate tumors, as it allows for a determination of the extent and nature of the lesion and local spread of the tumor. Carcinoma on pleomorphic adenoma in cervical salivary heteropia. Adenoma pleomorfo, paladar, glandula salival, tumor. Scribd is the worlds largest social reading and publishing site. The signs and symptoms are similar to other malignant salivary gland tumours. Pleomorphic adenomas account for 7080% of benign salivary gland tumors and are especially common in the parotid gland see below 1,6 patients are typically middle aged and the incidence is slightly higher in females than males 2. Pleomorphic adenoma pa is the most common salivary gland tumor, accounting for about 40%70% of all major and minor salivary gland tumors mgst. Adenoma pleomorfo detto anche tumore misto della parotide ciao, ho 28 anni e mi hanno diagnosticato l adenoma pleomorfo parotideo quando ne avevo solo 12. Submaxillary gland pleomorphic adenoma in teen and extirpation. Mostly, pa is located in the parotid glands 85%, minor salivary glands 10%, and the submandibular glands 5%.
Pleomorphic adenoma is a common benign salivary gland neoplasm characterised by neoplastic proliferation of parenchymatous glandular cells along with myoepithelial components, having a malignant potentiality. It arises from the benign tumour pleomorphic adenoma. They can attain giant proportions and weigh several kilograms. Principalmente afecta a las glandulas salivales mayores, y es mucho menos. It progresses slowly and, left untreated, can produce signi. Pleomorphic adenoma is the most common of all salivary gland neoplasms, at almost 50% of tumors.
Pleomorphic adenoma is the most common salivary gland tumor on the head and neck region 1. Its morphologic complexity results from differentiation of tumor cells. Pleomorphic adenoma, the most common salivary gland tumor, is also known as benign mixed tumors bmts, because of its dual origin from epithelial and myoepithelial elements. It is epithelially derived and typically presents as a cytologically benign circumscribed mass with variable encapsulation8, 9, 19, 21. Gitta madani, in maxillofacial surgery third edition, 2017. Codifica uma proteinas nao histona, relacionada a varios tumores. The stroma may be chondroid, myxoid, osteoid, or fibroid. Carcinoma ex pleomorphic adenoma is a rare, highly malignant tumor, accounting for 11.
The diagnosis is made by the clinical and histo pathological examination. May 29, 2019 adenoma is a non cancerous tumor that begins in the epithelium of mucosa or in the glands and ducts of the endocrine hormone producing glands or exocrine glands like sweat glands and glands in. There are three main patterns of malignant change that occur in pleomorphic adenoma. Nasal pleomorphic adenoma with skeletal muscle differentiation. Acomete tanto glandulas salivares menores quanto maiores. It derives its name from the architectural pleomorphism variable. Osseous pleomorphic adenoma tumor with bone formation many clinical conditions may have similar signs and symptoms. There are many diagnostic methods that can be used to determine the type of salivary gland tumour and if it is benign or malignant. The neoplasm most commonly involved in bilateral or multicentric simultaneous salivary gland location is the warthin tumour, while pleomorphic adenoma benign mixed tumour is the second most frequent.
Su localizacion predilecta es en glandula parotida. Pleomorphic adenoma of the salivary glands radiology. Pa most commonly occurs in the parotid gland but it may involve submandibular, lingual and minor salivary glands also. Metastasizing pleomorphic adenoma the term currently preferred by the world health organization who is also known as metastasizing. Pleomorphic adenoma, or benign mixed tumor, is the most common tumor of the parotid gland and represents 70% of all parotid neoplasms.
Morbidity increases due to the total displacement of the tumor without its capsule. Your healthcare provider may perform additional tests to rule out other clinical conditions to arrive at a definitive diagnosis. Pleomorphic adenoma, the most common salivary gland tumor, consists of epithelial and mesenchymal components. Pleomorphic adenoma presents as a painless and slowly growing mass and also as exophthalmoses. Histomorphically it is characterized by a variegated architecture comprising epithelial elements admixed with a mucoid, myxoid, fibrohyaline or chondroid stoma. The most common tumour of salivary gland is pleomorphic adenoma pa.
Atypical presentation of lacrimal gland pleomorphic adenoma. Adenoma pleomorfico by milca mabet mendoza ayala on prezi. Carcinoma ex pleomorphic adenoma ca ex pa is a type of cancer typically found in the parotid gland. Recurrent pleomorphic adenoma of submandibular region. E derivato dal significato di adeno di parola pertinente ad una ghiandola.
It is found mostly in the parotid gland in middleaged women. Pleomorphic adenoma pa is the most common benign tumor affecting both major and minor salivary glands. Adenoma pleomorfo cancer enfermedades y trastornos free. Abstract pleomorphic adenoma is the most common salivary gland tumour and accounts for about 60% of all salivary neoplasms. View and download powerpoint presentations on pleomorphic adenoma ppt. Carcinoma ex pleomorphic adenoma is the most common variety of mixed malignant tumor where carcinoma develops from the epithelial elements of a preexisting pleomorphic adenoma. External clinical examination showed a mass arising from the lateral wall of the right nasal cavity and filling the nasofacial furrow. Among minor salivary glands, palate is the most commonly affected site followed by lips, cheeks, gingiva, floor of the mouth, and tongue. The epithelial cells make up a trabecular pattern that is contained within a stroma.
However, the presence of this tumour should be suspected if there is a growth in said location, regardless of its presentation form. Salivary gland tumours account for 3% of the head and neck tumours. A pleomorphic adenoma is a benign overgrowth arising from the salivary gland tissue and it is a painless hard, mobile, solitary mass. Ledezma c, garces m, gomez l, fernandez r, jackques yn 2002 adenoma pleomorfo. Imaging characteristics of recurrent pleomorphic adenoma. A huge pleomorphic adenoma of the submandibular salivary. Histology of submandibular gland tumours, 10 years experience. Metastasizing pleomorphic adenoma is a rarely detected form of clinic antity 2,3. Simultaneous pleomorphic adenoma of the parapharyngeal. Non nascondo le mie paure in merito e mi fa piacere aver trovato questo forum di discussione. It is the most common type of salivary gland tumor and the most common tumor of the parotid gland. Surgical approach to a pleomorphic adenoma of the palate. According to the world health organisation the characteristic of this tumor is benign in histologically but distant or local metastasis are possible 3. On mriimages, the borders of parotid and submandibular gland.
Metastasizing pleomorphic adenoma is the third type of malignant mixed tumor of salivary glands and is the rarest. They are benign, painless, can grow into big tumours but usually do not affect nerves or lymph nodes. Pleomorphic adenoma of the lateral nasal wall 151 for 10 years, frontal cephalalgia and anosmia. Pleomorphic adenomas usually are slowgrowing painless masses. It usually develops from malignant transformation of a longstanding pleomorphic adenoma. Pleomorphic adenoma is the most common benign salivary gland neoplasm. The growth is usually mobile unless found in the palate and when found in the parotid tail, it is present as an eversion of the ear auricle. Pa is a benign mixed tumor composed of epithelial and myoepithelial cells arranged in various morphological patterns. Pleomorphic adenoma pa, also known as benign mixed tumor, is the most common salivary tumor, constituting up to twothirds of all salivary gland neoplasms. Sustained response of carcinoma ex pleomorphic adenoma. B adenoma pleomorfo, capsula fibroconectiva sin infiltracion, 10.
Surgical approach to a pleomorphic adenoma of the palate with. Glandulas salivales y funciones introduccion objetivos, metodologia y resultados anatomia metodologia objetivos lento 4. After paraclinical and pathologic evaluation, it was diagnosed as. Malignant salivary tumors represent 3 to 5% of all malignant head and neck tumors, with 2500 new cases diagnosed in the unites states yearly. It is the commonest of all salivary gland tumors constituting up. Malignant degeneration of an adenoma increases from 1. An important characteristic is that it is a tumour of variable and incomplete capsulation. Pa of buccal minor salivary glands is a very rare occurrence both in. Files are available under licenses specified on their description page. The pleomorphic adenoma pa is the most common benign neoplasia in salivary glands, affecting most commonly the parotid gland of females between the 4th and 6th decades of life. In the majority of cases, tumors originate in the superficial lobe. May 17, 2017 carcinoma ex adenoma pleomorfico embora a carcinogenese tenha sido investigada por diferentes metodos, o processo e altamente complexo e permanece obscuro translocacoes e rearranjos nos oncogenes hmga2 e mdm2. What are the possible complications of pleomorphic adenoma of salivary gland.
1403 1074 46 600 429 561 94 858 1383 845 1503 151 1315 1327 633 180 1438 400 1612 203 1142 1166 850 754 1481 186 371 1215 261 210 390 1011 971 431 1434 653 1069 1304 1043